Thanks to new treatments, cancer death rates have decreased by 22%!

cancer-cellStating that there has been a 22% decrease in cancer death rates thanks to the new treatment options that have come into use in recent years, Acıbadem University, Department of Internal Medicine/Medical Oncology faculty member Prof. Dr. Gül Başaran stated that if the preventive measures against cancer are evaluated in the broadcast, significant success can be achieved. Stating that vital changes in many types of cancer can be prevented with vaccine treatments or timely treatment of infections, Prof. Dr. Gül Başaran says that with early diagnosis, the tumor is surgically removed while it is small, and patients are provided with a longer chance of survival, and that in many cancers that are diagnosed early and treated duly, it is possible to live until the end of life without the disease coming back.

Cancer, which is the name given to a group of diseases that can affect any organ in our body, is basically formed by the uncontrolled proliferation of cells that gain the character of division on their own, ignoring the body’s protection mechanisms. The conditions that make cancer, which has more than 100 types, deadly, are the spread (metastasis) from the organ in which it is located, to other organs through the blood.

Opinions received due to cancer week prof. Dr. Rose BasaranNoting that it is estimated that 30 percent of cancer-related deaths are associated with obesity, smoking, insufficient physical activity, excessive alcohol consumption and malnutrition, he draws attention to the following points: “20 percent of all cancer deaths and 70 percent of deaths from lung cancer. linked to smoking. Some cancers develop with infectious agents such as HPV, Hepatitis B, Hepatitis C, HIV or Helicobacter Pylori.”

Most common cancers

Despite all the ongoing positive developments in cancer treatment, cancer is still a global health problem. According to the 2012 report of the World Health Organization, the annual number of newly diagnosed cancer patients is approximately 14 million and this number is expected to increase to 22 million in the next twenty years. Most common cancers: lung cancer (1.8 million cases, 13 percent of all cancers), breast cancer (11.9 percent of 1.7 million cancers), bowel cancer (1.4 million, 9 percent of all cancers) ,7 of them). The most common cancers in men are lung, prostate, bowel, stomach and liver cancers; The most common cancers seen in women are breast, bowel, lung, cervix and stomach cancers. There may be differences in this ranking according to the development status and geographical location of the countries.

The number of deaths from cancer is about 8.2 million per year. Stating that this number is estimated to increase to 13 million in the next twenty years, Prof. Dr. Gül Başaran, lung cancer (1.6 million, 19.4% of all cancer deaths), liver cancer (0.8 million, 9.1% of all cancer deaths), stomach cancer (0, 7 million, 8.8% of all cancer deaths), bowel cancer (0.7 million) and breast cancer (0.5 million).

Seven important signs of cancer!

The importance of preventive studies and early diagnosis cannot be overemphasized!

Developing countries are the most affected by the cancer problem. 60% of cancers in the world are found in Africa, Asia, Central and South America. Cancer deaths in these regions account for 70% of cancer deaths worldwide. Stating that this situation is related to the lack of early diagnosis and the inability to reach appropriate treatments, Prof. Dr. Gül Başaran said, “Furthermore, when today’s information is used properly, half of cancers can be prevented. For this reason, studies on disease prevention as well as treatment are inevitable to achieve good results in this disease group,” he continues with a hopeful expression: “In developed societies, with effective treatments and modern living conditions, many cancers have been experienced and those who continue their lives (cancer) survivors) people. For example, in the United States, it is known that there are about 15 million people who have had cancer and continue to live.”

Early diagnosis allows surgical removal of the tumor while it is still small, thus providing patients with a longer life expectancy. In many cancers that are diagnosed early and treated duly, it is possible to cure/heal, that is, to live until the end of life without the disease coming back. prof. Dr. Gül Başaran draws attention to the following points for early diagnosis: “For example, a change in defecation or urination habits, sore throat that does not heal, hoarseness or cough that does not go away, unexpected bleeding or discharge, feeling a mass in our organs, difficulty in swallowing, the size of an existing mole. When there is a change in shape and color, it is necessary to consult a doctor. However, this does not mean that everyone with these symptoms has cancer, because there are many non-cancerous diseases that cause the same markers. Cancer diagnosis should be excluded with examinations.”

One of the most important factors in early diagnosis is screening tests. Below are the tests that healthy people should have for early diagnosis for certain cancers:

  • Annual mammogram after age 40 for breast cancer
  • Colonoscopy every 10 years after age 50 for colon cancer
  • Every 3 years between the ages of 21-65 for cervical cancer; PAP test should be done between the ages of 30-65, PAP test should be stopped in women who have 3 consecutive negative PAP tests over the age of 66.
  • For lung cancer, it is appropriate to screen with low-dose lung tomography only in people with a 30-year smoking history, who are considered to be high-risk, and currently smoke or have not smoked for the last 15 years.
  • Screening with PSA for prostate cancer after the age of 50 is left to the patient’s discretion.

Aging is also the most important risk factor for cancer development. Because with aging, our cell repair mechanisms work less, so our ability to destroy damaged cells that have the characteristics of becoming cancer decreases.

prof. Dr. Gül Başaran emphasizes that more than 30 percent of cancers can be prevented only by making changes in our lifestyle to eliminate the following risk factors.

  • smoking
  • Obesity
  • Improper diet (lack of fruit and vegetables)
  • living without physical activity
  • drinking alcohol
  • sexually transmitted diseases (HPV)
  • hepatitis B infection
  • Air pollution
  • Exposure to non-ionizing (such as the sun) or ionizing radiation (such as occupational, radiation)

prof. Dr. Gül Başaran said, “Cancers caused by these factors can be prevented with vital changes, vaccination treatments and treatment of infection. A significant portion of skin cancers can occur from too much sun exposure or solarium, so you should go out to the sun at appropriate times,” he warns.

cancer treatment research

Investments in the development of new cancer-related treatments have increased worldwide. The pharmaceutical industry spent $51 billion on drug research and development in 2014. It is stated that since the war on cancer started in the 1970s, there has been a 22% decrease in cancer deaths, and 80% of this is due to new treatments.

Advances in cancer treatment have been accelerated mainly by a better understanding of cancer biology. The scientific technology learned in the Human Genome Project (the project that envisions DNA mapping) and the fact that clinicians observed that patients with similar tumor characteristics who received the same treatment followed a different clinical course showed that everyone’s cancer is unique. Some molecular changes detected in the patient’s tumor can show both how that cancer will progress and what types of treatments it will respond to. The molecular factors that enable the survival and progression of the tumor discovered in the last 15 years and the targeted therapy drugs developed against them have started a new era in cancer treatment. These treatments, which we apply today as tumor-specific treatment, have enabled us to achieve satisfactory results in many cancer types such as breast, lung, colon, melanoma, head and neck cancers, and lymphoma.

prof. Dr. Gül Başaran adds the following regarding treatments, “One of the most interesting cancer treatment methods in recent years has been the drug groups that we call immunotherapy, which enable the person to fight the tumor by activating his/her own immune system. In many cancers, it was known that our immune cells, which are related to destroying cancer, do not work or work insufficiently for various reasons. If we compare the immune system to an army, sometimes this army does not have enough equipment against tumors, sometimes there are problems with the army being called to duty, sometimes the army cannot overcome an obstacle, and sometimes the army is lazy and cannot fulfill its duty. With immunotherapy, which allows our defense cells to effectively fight cancer cells by overcoming these disorders, successful results were obtained in melanoma, which we could not achieve with many treatment types for 30 years, and then in many solid cancer types such as lung cancer, kidney tumors and lymphoma. They succeeded in taking the first place among the treatment options. The question of how we can use immunotherapy most effectively is still being investigated.”

3 new therapies to delay recurrence in breast cancer…

Acıbadem University, Department of Internal Medicine/Medical Oncology faculty member Prof. Dr. Rose Basaran,

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