New drugs increase success in Chronic Myeloid Leukemia treatment

how to stop nosebleedCML (Chronic Myeloid Leukemia), which is among the slow-growing cancer types, has ceased to be a deadly disease with new treatment methods. CML (Chronic Myeloid Leukemia) disease, in which an average of 550 people are caught every year in Turkey, occurs with symptoms such as extreme fatigue, spleen enlargement and bone pain, and can be treated in a way that ensures a long and quality life with good follow-up and the right treatment. Turkish Hematology Association (THD) President Prof. Dr. Teoman Soysal; He gave comprehensive information about what is CML, Chronic Myeloid Leukemia, its symptoms, diagnosis and treatment.

Chronic myeloid leukemia, a bone marrow and blood disease in which an average of 550 people are diagnosed every year in Turkey, can reach a level that can lead to fatal results within 2-3 years if diagnosis and treatment are neglected. Although it can be seen in all age groups, CML is one of the slow-growing cancer types that most commonly occurs between the ages of 50-60 and may not be noticed by patients in its early stages. As the disease progresses, symptoms such as extreme fatigue, night sweats, spleen enlargement, bone pain, fullness in the left part of the abdomen and weight loss can be seen.

Leukemia (blood cancer) symptoms and new treatment options

In approximately 40% of CML patients, high leukocyte values ​​that occur incidentally in the blood count can also help the diagnosis. Since all these symptoms are also seen in many different diseases, the diagnosis of CML requires an examination based on the patient’s symptoms, complete blood count, microscopic examinations, and genetic and molecular tests showing chromosomal aberrations.

What kind of disease is Chronic Myeloid Leukemia, is it possible to treat?

“CML disease occurs as a result of the reciprocal displacement of parts of the 9th and 22nd chromosomes,” said Prof. Dr. Teoman Soysal emphasizes that this chromosomal defect causes changes in intracellular mechanisms, and especially white blood cells are affected. CML is a slow-progressing type of leukemia that results in excessive proliferation of cells in the bone marrow, and if left untreated, it can turn into a fatal disease with no cure within 3-6 years. It may be possible to manage CML, which is not a hereditary disease transmitted from generation to generation, with correct diagnosis and timely treatment processes.

The date of September 22, which symbolizes the place of chromosome numbers in the calendar, was declared as “International CML Day” in 2011 due to the genetic change in chromosomes 9 and 22 that causes CML. Reminding that awareness-raising activities are carried out on CML every year on September 22, Prof. Dr. Teoman Soysal states that complete blood count, microscopic examinations, and genetic and molecular tests that reveal typical chromosomal disorders should not be neglected in the diagnosis and follow-up of CML.

The survival time of patients is increasing rapidly with new generation leukemia treatments

Chronic Myeloid Leukemia, early diagnosis, good follow-up and correct treatment

Soysal states that thanks to the treatments developed in the fight against the disease, more and more CML patients are able to reach a health condition that can continue to live their lives every year. “Twenty years ago, CML was a potentially fatal disease. With the development of targeted therapies, we can say that CML has now become manageable and the life expectancy of patients has been extended. Dr. Teoman Soysal underlines that the key elements in the treatment of CML are early diagnosis, good follow-up and correct treatment. Soysal adds, “Today, CML patients can lead a quality and long life thanks to drugs that target intracellular changes in CML treatment.”

Effective approach in the treatment of CML: Molecular Monitoring

Disease follow-up, which is one of the most effective elements in the treatment of CML, can be done more effectively thanks to the molecular methods of examining the intracellular disorder in patients. This method is also called “molecular monitoring”. In Turkey, the rate of patients who can get results at the molecular response level is around 85%. Thanks to this method, physicians can follow the progression of the disease in a standard format and perform the treatment of this slow-growing cancer type more effectively.

The incidence of CML in Western countries is measured as one in 100,000. There are approximately 2,800 CML patients in Turkey. If detected early, followed up well and new treatment options are applied, CML patients can lead a quality and long life.

Success rates in acute leukemia treatment have reached 90 percent



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yusuf karakaya

yusuf karakaya

1 year ago

a good life for everyone, there are various treatments for various diseases for a good life and it is a very useful website for those who like to research like me.

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